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Clinical Evidence and Methodology

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

When to Use

  • Evaluation of suspected Acute Myocardial Infarction (AMI) in patients with a Left Bundle Branch Block (LBBB).
  • To differentiate baseline LBBB ST-changes from acute ischemia.
  • In patients with ventricularly paced rhythms (pacemaker).
CLINICAL INSIGHT

How it Works

The Rule of Discordance

In normal LBBB, the ST segment and T wave should be "discordant" (opposite) to the main QRS deflection. Sgarbossa criteria identify AMI by looking for "concordance" (ST deviation in the same direction as the QRS) or "excessive discordance."

Scoring Criteria

Concordant ST elevation ≥ 1 mm in any lead
Concordant ST depression ≥ 1 mm in lead V1, V2, or V3
Discordant ST elevation ≥ 5 mm in leads with negative QRS

Interpretation

A score ≥ 3 has a specificity of ~98% for AMI, though sensitivity is low (~20-30%).

CLINICAL INSIGHT

Practical Pearls

LBBB = STEMI?

Recent ESC and AHA guidelines no longer consider "new LBBB" alone as a STEMI equivalent unless symptoms are refractory. Sgarbossa criteria help identify the subset of LBBB patients who truly have an occluded artery and need the cath lab.

CLINICAL INSIGHT

Next Steps

Complementary Calculators

CLINICAL INSIGHT

Evidence Base

Original Study

Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block.

Sgarbossa EB, et al.N Engl J Med.1996

Sgarbossa Criteria

Sgarbossa Criteria: Used to identify acute myocardial infarction (AMI) in the presence of Left Bundle Branch Block (LBBB) or ventricular paced rhythm. A score ≥ 3 is highly specific for AMI.

Criteria Assessment

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

When to Use

  • Evaluation of suspected Acute Myocardial Infarction (AMI) in patients with a Left Bundle Branch Block (LBBB).
  • To differentiate baseline LBBB ST-changes from acute ischemia.
  • In patients with ventricularly paced rhythms (pacemaker).
CLINICAL INSIGHT

How it Works

The Rule of Discordance

In normal LBBB, the ST segment and T wave should be "discordant" (opposite) to the main QRS deflection. Sgarbossa criteria identify AMI by looking for "concordance" (ST deviation in the same direction as the QRS) or "excessive discordance."

Scoring Criteria

Concordant ST elevation ≥ 1 mm in any lead
Concordant ST depression ≥ 1 mm in lead V1, V2, or V3
Discordant ST elevation ≥ 5 mm in leads with negative QRS

Interpretation

A score ≥ 3 has a specificity of ~98% for AMI, though sensitivity is low (~20-30%).

CLINICAL INSIGHT

Practical Pearls

LBBB = STEMI?

Recent ESC and AHA guidelines no longer consider "new LBBB" alone as a STEMI equivalent unless symptoms are refractory. Sgarbossa criteria help identify the subset of LBBB patients who truly have an occluded artery and need the cath lab.

CLINICAL INSIGHT

Next Steps

Complementary Calculators

CLINICAL INSIGHT

Evidence Base

Original Study

Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block.

Sgarbossa EB, et al.N Engl J Med.1996