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Clinical Evidence and Methodology

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

When to Use

  • Differential diagnosis of wide complex tachycardia (WCT) where the underlying rhythm is unclear.
  • As a fast, single-lead (aVR) alternative to the 4-step Brugada criteria.
  • Particularly useful when precordial leads (V1-V6) are unavailable or difficult to interpret.

Clinical Caveat

Any wide complex tachycardia in an unstable patient should be treated as VT regardless of algorithm results. Synchronized cardioversion is the priority.

CLINICAL INSIGHT

How it Works

Why lead aVR?

During SVT with bundle branch block, the initial activation of the ventricles occurs via the normal specialized conduction system, which typically moves AWAY from lead aVR (creating a negative QRS). In VT, activation often starts in the inferior/apical regions and moves TOWARD aVR, or is slowed by muscle-to-muscle conduction.

The 4 Steps

  • Presence of an initial R wave: Highly specific for VT.
  • Initial r or q wave width > 40 ms: Suggests slow muscle-to-muscle conduction diagnostic of VT.
  • Notch on the descending limb of a negative QRS: Indicates fragmented ventricular activation.
  • Vi/Vt ratio ≤ 1: Measures the velocity of initial activation (Vi) vs terminal activation (Vt) in the last 40ms. SVT is fast initially (Ratio > 1), VT is slow initially (Ratio ≤ 1).
CLINICAL INSIGHT

Practical Pearls

Accuracy vs Brugada

The Vereckei algorithm has shown slightly higher overall accuracy than Brugada in some head-to-head trials, mainly due to its better performance in diagnosing VT in patients with pre-existing bundle branch blocks or cardiomyopathy.

CLINICAL INSIGHT

Evidence Base

Original Publication

New algorithm using only lead aVR for differential diagnosis of wide QRS complex tachycardia.

Vereckei A, Miller GW, Miller JM, et al.Heart Rhythm.2008

Vereckei Algorithm

Vereckei Algorithm: A simplified, lead aVR-only algorithm to differentiate Ventricular Tachycardia (VT) from Supraventricular Tachycardia (SVT) with aberrancy.

Examine Lead aVR Only

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

When to Use

  • Differential diagnosis of wide complex tachycardia (WCT) where the underlying rhythm is unclear.
  • As a fast, single-lead (aVR) alternative to the 4-step Brugada criteria.
  • Particularly useful when precordial leads (V1-V6) are unavailable or difficult to interpret.

Clinical Caveat

Any wide complex tachycardia in an unstable patient should be treated as VT regardless of algorithm results. Synchronized cardioversion is the priority.

CLINICAL INSIGHT

How it Works

Why lead aVR?

During SVT with bundle branch block, the initial activation of the ventricles occurs via the normal specialized conduction system, which typically moves AWAY from lead aVR (creating a negative QRS). In VT, activation often starts in the inferior/apical regions and moves TOWARD aVR, or is slowed by muscle-to-muscle conduction.

The 4 Steps

  • Presence of an initial R wave: Highly specific for VT.
  • Initial r or q wave width > 40 ms: Suggests slow muscle-to-muscle conduction diagnostic of VT.
  • Notch on the descending limb of a negative QRS: Indicates fragmented ventricular activation.
  • Vi/Vt ratio ≤ 1: Measures the velocity of initial activation (Vi) vs terminal activation (Vt) in the last 40ms. SVT is fast initially (Ratio > 1), VT is slow initially (Ratio ≤ 1).
CLINICAL INSIGHT

Practical Pearls

Accuracy vs Brugada

The Vereckei algorithm has shown slightly higher overall accuracy than Brugada in some head-to-head trials, mainly due to its better performance in diagnosing VT in patients with pre-existing bundle branch blocks or cardiomyopathy.

CLINICAL INSIGHT

Evidence Base

Original Publication

New algorithm using only lead aVR for differential diagnosis of wide QRS complex tachycardia.

Vereckei A, Miller GW, Miller JM, et al.Heart Rhythm.2008