YMRS: Young Mania Rating Scale. 11-item clinician-administered scale. 4 items (5,6,8,9) scored on 0–8 scale; 7 items on 0–4. Total 0–60. Standard endpoint in mania therapy trials.
1. Elevated Mood
0 — Absent1 — Mildly or possibly increased on questioning2 — Definite subjective elevation; optimistic, self-confident; cheerful3 — Elevated; inappropriate to content; harmonious4 — Euphoric; inappropriate laughter; singing
2. Increased Motor Activity–Energy
0 — Absent1 — Subjectively increased2 — Animated; gestures increased3 — Excessive energy; hyperactive at times; restless (can be calmed)4 — Motor excitement; continuous hyperactivity (cannot be calmed)
3. Sexual Interest
0 — Normal; not increased1 — Mildly or possibly increased2 — Definite subjective increase on questioning3 — Spontaneous sexual content; elaborates on sexual matters; hypersexual by self-report4 — Overt sexual acts or urges; sexually explicit
4. Sleep
0 — Reports no decrease in sleep1 — Sleeping less than normal amount by up to 1 hour2 — Sleeping less than normal by more than 1 hour3 — Reports decreased need for sleep4 — Denies need for sleep
5. Irritability
0 — Absent2 — Subjectively increased4 — Irritable at times during interview; recent episodes of anger or annoyance on ward6 — Frequently irritable during interview; short, curt throughout8 — Hostile, uncooperative; interview impossible
6. Speech (Rate and Amount)
0 — No increase2 — Feels talkative4 — Increased rate or amount at times; verbose at times6 — Push; consistently increased rate and amount; difficult to interrupt8 — Pressured; uninterruptible; continuous speech
7. Language–Thought Disorder
0 — Absent1 — Circumstantial; mild distractibility; quick thoughts2 — Distractible; loses goal of thought; changes topics frequently; racing thoughts3 — Flight of ideas; tangentiality; difficult to follow; rhyming, echolalia4 — Incoherent; communication impossible
8. Content
0 — Normal2 — Questionable plans; new interests4 — Special project; hyperreligious6 — Grandiose or paranoid ideas; ideas of reference8 — Delusions; hallucinations
9. Disruptive–Aggressive Behaviour
0 — Absent; cooperative2 — Sarcastic; loud at times; guarded4 — Demanding; threats on ward6 — Threatens interviewer; shouting; interview difficult8 — Assaultive; destructive; interview impossible
10. Appearance
0 — Appropriate dress and grooming1 — Slightly unkempt2 — Poorly groomed; moderately disheveled; overdressed3 — Disheveled; partly clothed; garish makeup4 — Completely unkempt; decorated; bizarre garb
11. Insight
0 — Present; admits illness; agrees with need for treatment1 — Possibly ill2 — Admits behaviour change, but denies illness3 — Admits possible change, but denies illness4 — Denies any behaviour change