Curated insights • How it Works • Practical Pearls • Evidence Base
CLINICAL INSIGHT
When to Use
When to Use
Evaluating the severity of atopic dermatitis (eczema) objectively.
Monitoring disease progression and treatment response over time.
Standardized reporting in clinical trials for atopic dermatitis therapies.
CLINICAL INSIGHT
How it Works
Formula
Variables
A: Extent of disease as percentage of Body Surface Area (BSA) affected (0-100).
B: Intensity of 6 specific morphologic lesions (erythema, edema/papulation, oozing/crusts, excoriations, lichenification, and dryness/xerosis) graded 0-3. Max 18.
C: Subjective symptoms (pruritus and sleep loss) over the last 3 days, graded 0-10 on VAS. Max 20.
CLINICAL INSIGHT
Practical Pearls
Clinical Pearls
Dryness (xerosis) is evaluated ONLY on uninvolved skin areas.
It combines both objective physician assessment and subjective patient-reported outcomes, making it very comprehensive.
A score > 50 indicates severe atopic dermatitis.
CLINICAL INSIGHT
Next Steps
Interpretation
< 25: Mild disease.
25 - 50: Moderate disease.
> 50: Severe disease. Consider escalation to systemic immunosuppression or biologics.