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7-Point Dermoscopy ChecklistAJCC Melanoma Staging (8th Ed)ALDEN Algorithm (Drug Causality for SJS/TEN)BWH High-Risk SCC StagingBody Surface Area (BSA)Breslow Thickness and Clark LevelDLQIEASI ScoreMSK Melanoma NomogramMelanoma RiskPASI ScorePOEM (Patient-Oriented Eczema Measure)RegiSCAR Criteria for DRESSSCORADSCORTENmPASI (Modified PASI)

Clinical Evidence and Methodology

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

When to Use

  • To measure atopic eczema severity directly from the patient’s perspective.
  • Standardized monitoring for atopic dermatitis (AD) in clinical practice and trials over the previous 7 days.
CLINICAL INSIGHT

How it Works

Scoring Logic

  • Consists of 7 questions about frequency of symptoms over the past week.
  • Symptoms evaluated: Itching, sleep disturbance, bleeding, weeping/oozing, cracking, flaking, feeling dry/rough.
  • Frequency scoring: No days (0), 1-2 days (1), 3-4 days (2), 5-6 days (3), Every day (4).

Interpretation

ScoreSeverity
0-2Clear or almost clear
3-7Mild eczema
8-16Moderate eczema
17-24Severe eczema
25-28Very severe eczema
CLINICAL INSIGHT

Practical Pearls

Clinical Pearls

  • Essential for capturing subjective disease burden (itch and sleep loss) that objective scores like EASI notoriously miss.
  • Requires the patient or parent/guardian to complete it independently prior to the consultation for maximum validity.
CLINICAL INSIGHT

Next Steps

Clinical Follow-up

A change of 3.4 points (often rounded to 3 or 4) is generally considered the Minimal Clinically Important Difference (MCID).

CLINICAL INSIGHT

Evidence Base

Primary Reference

SCORAD

SCORAD Index: Unified assessment of Atopic Dermatitis severity (Area, Intensity, Symptoms).
0%0%100%

erythema

edema

crusting

excoriation

lichenification

dryness

0010
0010
EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

When to Use

  • Evaluating the severity of atopic dermatitis (eczema) objectively.
  • Monitoring disease progression and treatment response over time.
  • Standardized reporting in clinical trials for atopic dermatitis therapies.
CLINICAL INSIGHT

How it Works

Formula

Variables

  • A: Extent of disease as percentage of Body Surface Area (BSA) affected (0-100).
  • B: Intensity of 6 specific morphologic lesions (erythema, edema/papulation, oozing/crusts, excoriations, lichenification, and dryness/xerosis) graded 0-3. Max 18.
  • C: Subjective symptoms (pruritus and sleep loss) over the last 3 days, graded 0-10 on VAS. Max 20.
CLINICAL INSIGHT

Practical Pearls

Clinical Pearls

  • Dryness (xerosis) is evaluated ONLY on uninvolved skin areas.
  • It combines both objective physician assessment and subjective patient-reported outcomes, making it very comprehensive.
  • A score > 50 indicates severe atopic dermatitis.
CLINICAL INSIGHT

Next Steps

Interpretation

  • < 25: Mild disease.
  • 25 - 50: Moderate disease.
  • > 50: Severe disease. Consider escalation to systemic immunosuppression or biologics.