• To predict the mortality risk in patients with Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN).
• To guide triage decisions (e.g., admitting to an ICU or specialized Burn Unit).

• Age > 40 years
• Heart rate > 120 beats/minute
• Presence of malignancy (cancer)
• Body surface area (BSA) detached or compromised > 10% on Day 1
• Blood Urea Nitrogen (BUN) > 28 mg/dL (>10 mmol/L)
• Serum Glucose > 252 mg/dL (>14 mmol/L)
• Serum Bicarbonate < 20 mEq/L

• Score 0-1: ~3.2%
• Score 2: ~12.1%
• Score 3: ~35.3%
• Score 4: ~58.3%
• Score ≥ 5: >90%

• Must be calculated within the first 24 hours of admission, and ideally repeated on Day 3 for the most accurate prognostic trajectory.
• Heavily weights end-organ stress (tachycardia, uremia, acidosis, hyperglycemia) rather than purely dermatologic signs.

Scores ≥ 2 warrant immediate transfer to a specialized Burn Center or Medical ICU, early ophthalmologic consultation, and cessation of all suspected offending drugs.