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Clinical Evidence and Methodology

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

Primary Clinical Uses

  • Standardized visual assessment to quantify the severity of hirsutism in women
  • Fulfilling the clinical hyperandrogenism criteria for the diagnosis of Polycystic Ovary Syndrome (PCOS)
  • Monitoring therapeutic response to anti-androgen treatments or oral contraceptives

Patient Context

Hirsutism (excess terminal hair in a male-pattern distribution) is distinct from hypertrichosis (generalized excess hair everywhere). The FG score exclusively targets androgen-sensitive regions to differentiate the two.

CLINICAL INSIGHT

How it Works

Scoring Logic

Evaluates terminal (dark, coarse) hair growth across 9 androgen-sensitive body areas. Each area is assigned a score from 0 (no terminal hair) to 4 (extensive visible hair). Maximum score is 36.

The 9 Assessment Areas

Upper Lip
Chin
Chest
Upper Back
Lower Back
Upper Abdomen
Lower Abdomen
Upper Arms
Thighs
CLINICAL INSIGHT

Practical Pearls

Key Nuances

  • Highly subjective tool with notable inter-observer variability.
  • Recent hair removal (shaving, plucking, waxing, laser) drastically masks the true baseline score. Patients should ideally not perform hair removal for 4 weeks prior to assessment.
  • Racial and ethnic variations are critical: The normal density of body hair varies wildly by genotype. Standard cutoffs may drastically overdiagnose or underdiagnose hirsutism depending on the patient's heritage.

Modifications

The original 1961 score included 11 body parts. The "Modified" Ferriman-Gallwey score (mFG), universally used today, removed the lower leg and forearm areas, as hair in those regions is typically independent of androgen levels.

CLINICAL INSIGHT

Next Steps

Interpretation and Action

  • Calculate total mFG Score.
  • Determine clinical hirsutism based on general cutoff (commonly ≥8, though ≥4-6 may be used in certain ethnic populations like East Asian women).
  • If positive and accompanying oligo/anovulation or PCO morphology: Meets Rotterdam criteria for PCOS.
  • Order biochemical evaluation: Total and Free Testosterone, DHEAS, 17-OH Progesterone (to rule out CAH).
  • If virilization is rapid or severe: Immediately screen for androgen-secreting ovarian or adrenal neoplasms.
CLINICAL INSIGHT

Evidence Base

Landmark References

Clinical assessment of body hair growth in women.

Ferriman D, Gallwey JD.J Clin Endocrinol Metab.1961

Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline.

Martin KA, et al.J Clin Endocrinol Metab.2018
CLINICAL INSIGHT

Background

Creators

Developed by Dr. David Ferriman and Dr. J.D. Gallwey in 1961. The current modified version (which dropped 2 regions to establish the 9-region standard) was later refined by Hatch et al. in 1981.

Ferriman-Gallwey Score

Modified Ferriman-Gallwey

Hirsutism Score

0

NORMAL HAIR DISTRIBUTION

Validated for most ethnicities (Cut-off ≥8). Smaller thresholds may apply to certain populations (e.g. East Asian).

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

Primary Clinical Uses

  • Standardized visual assessment to quantify the severity of hirsutism in women
  • Fulfilling the clinical hyperandrogenism criteria for the diagnosis of Polycystic Ovary Syndrome (PCOS)
  • Monitoring therapeutic response to anti-androgen treatments or oral contraceptives

Patient Context

Hirsutism (excess terminal hair in a male-pattern distribution) is distinct from hypertrichosis (generalized excess hair everywhere). The FG score exclusively targets androgen-sensitive regions to differentiate the two.

CLINICAL INSIGHT

How it Works

Scoring Logic

Evaluates terminal (dark, coarse) hair growth across 9 androgen-sensitive body areas. Each area is assigned a score from 0 (no terminal hair) to 4 (extensive visible hair). Maximum score is 36.

The 9 Assessment Areas

Upper Lip
Chin
Chest
Upper Back
Lower Back
Upper Abdomen
Lower Abdomen
Upper Arms
Thighs
CLINICAL INSIGHT

Practical Pearls

Key Nuances

  • Highly subjective tool with notable inter-observer variability.
  • Recent hair removal (shaving, plucking, waxing, laser) drastically masks the true baseline score. Patients should ideally not perform hair removal for 4 weeks prior to assessment.
  • Racial and ethnic variations are critical: The normal density of body hair varies wildly by genotype. Standard cutoffs may drastically overdiagnose or underdiagnose hirsutism depending on the patient's heritage.

Modifications

The original 1961 score included 11 body parts. The "Modified" Ferriman-Gallwey score (mFG), universally used today, removed the lower leg and forearm areas, as hair in those regions is typically independent of androgen levels.

CLINICAL INSIGHT

Next Steps

Interpretation and Action

  • Calculate total mFG Score.
  • Determine clinical hirsutism based on general cutoff (commonly ≥8, though ≥4-6 may be used in certain ethnic populations like East Asian women).
  • If positive and accompanying oligo/anovulation or PCO morphology: Meets Rotterdam criteria for PCOS.
  • Order biochemical evaluation: Total and Free Testosterone, DHEAS, 17-OH Progesterone (to rule out CAH).
  • If virilization is rapid or severe: Immediately screen for androgen-secreting ovarian or adrenal neoplasms.
CLINICAL INSIGHT

Evidence Base

Landmark References

Clinical assessment of body hair growth in women.

Ferriman D, Gallwey JD.J Clin Endocrinol Metab.1961

Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline.

Martin KA, et al.J Clin Endocrinol Metab.2018
CLINICAL INSIGHT

Background

Creators

Developed by Dr. David Ferriman and Dr. J.D. Gallwey in 1961. The current modified version (which dropped 2 regions to establish the 9-region standard) was later refined by Hatch et al. in 1981.