Universal Emergency Response Framework
Immediate Actions
Pharmacotherapy
Refractory Care
Uterine Balloon (UBT) • NASG Garment • Surgery. If Shock Index persists > 1.1 → ACTIVATE MTP.
Curated insights • How it Works • Practical Pearls • Evidence Base
Cumulative blood loss ≥1,000 mL or blood loss accompanied by signs or symptoms of hypovolemia within 24 hours after the birth process (includes intrapartum loss) regardless of route of delivery.
| Tone (Atony) |
| Tissue (Retained products) |
| Trauma (Lacerations/Inversion) |
| Thrombin (Coagulopathy) |
| Oxytocin (Pitocin) |
| Methylergonovine (Methergine) |
| 15-methyl PGF2α (Hemabate) |
| Misoprostol (Cytotec) |
| Tranexamic Acid (TXA) |
Methergine is absolutely contraindicated in hypertensive disorders (Preeclampsia, Chronic HTN). Hemabate (Carboprost) is contraindicated in patients with reactive airway disease/asthma.
Practice Bulletin No. 183: Postpartum Hemorrhage.
Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage.
The Association of Women's Health, Obstetric and Neonatal Nurses (AWHONN) emphasizes that standardized unit protocols and drills significantly reduce maternal morbidity.
Postpartum hemorrhage remains the leading cause of maternal mortality worldwide. Modern "Stage-Based" protocols were developed to replace the chaotic "reflexive" management of the past with a structured, multidisciplinary approach similar to ACLS.
The California Maternal Quality Care Collaborative (CMQCC) was instrumental in developing the toolkits that pioneered the use of QBL (Quantified Blood Loss) and standardized PPH carts, which are now global standards.