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PAS Hemorrhage Risk

PAS Spectrum Risk

Placenta Accreta / Increta / Percreta Assessment

High-Yield Ultrasound Markers

  • Prior Cesarean Section (Weighted Rank 1)
  • Placenta Previa (Co-existing)
  • Multiple Placental Lacunae
  • Loss of retroplacental clear zone
  • Abnormal uterine-bladder interface
  • Exophytic mass (Extra-uterine extension)

Massive Transfusion (MTP)

WHO/FIGO Aligned Protocol: 1:1:1 Ratio (RBC : FFP : Platelets).

Hb Target> 7g/dL
Plt Target> 50k
Fib Target> 200mg/dL
Critical Bleeding RateExceeding 150mL / Minute
EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

Primary Clinical Uses

  • Classifying the profound morbidity risk in patients presenting with placenta previa and prior cesarean sections.
  • Directing surgical planning (e.g., scheduled cesarean hysterectomy, massive transfusion protocols).
  • Pre-operative counseling regarding the extreme risk of catastrophic pelvic hemorrhage.

What is PAS?

Placenta Accreta Spectrum (PAS) involves abnormal trophoblast invasion into the myometrium. It is categorized into Accreta (attaches directly to myometrium), Increta (invades into myometrium), and Percreta (penetrates through serosa/bladder).

CLINICAL INSIGHT

How it Works

Risk Amplification (Silver et al.)

Calculated Risk with Placenta Previa:
0 Prior Cesareans
1 Prior Cesarean
2 Prior Cesareans
3 Prior Cesareans
4+ Prior Cesareans

Key Ultrasound Markers

  • Multiple irregular placental lacunae ("Swiss cheese" appearance)
  • Loss of the normal retroplacental clear space
  • Myometrial thickness < 1 mm
  • Bridging vessels spanning from placenta into bladder wall (Percreta)
CLINICAL INSIGHT

Practical Pearls

Absolute Contraindications

  • DO NOT attempt manual removal of the placenta if PAS is aggressively suspected or confirmed intraoperatively. Forcing a cleavage plane will trigger instant, massive, and virtually uncontrollable pelvic hemorrhage.
  • If diagnosed unexpectedly upon opening the abdomen during a routine C-section, do not disturb the placenta. Close the hysterotomy, pack the abdomen if needed, and call immediately for Gynecologic Oncology or a highly experienced surgical rescue team.
CLINICAL INSIGHT

Next Steps

Surgical Pathway (Confirmed Increta/Percreta)

  • Schedule controlled delivery at 34 0/7 to 35 6/7 weeks.
  • Assemble multidisciplinary team: MFM, Gyn Oncology, Urologist (for ureteral stents), Trauma/Transfusion Medicine.
  • Perform classical (vertical) hysterotomy vastly superior to the placental edge to deliver the infant without cutting through the placenta.
  • Leave placenta strictly *in situ* undisturbed.
  • Proceed directly to total hysterectomy with the placenta still inside the uterus.
CLINICAL INSIGHT

Evidence Base

Landmark References

Maternal morbidity associated with multiple repeat cesarean deliveries.

Silver RM, Landon MB, Rouse DJ, et al.Obstet Gynecol.2006

Placenta Accreta Spectrum.

ACOG Obstetric Care Consensus No. 7.Obstet Gynecol.2018
CLINICAL INSIGHT

Background

A Man-Made Epidemic

Placenta Accreta was exceptionally rare before the 1980s. The colossal rise in global cesarean section delivery rates created a man-made pathological phenomenon where fertilized eggs preferentially implant over scarred, defective anterior lower uterine segment tissue.