OpiCalc Logo

OpiCalc

--- Clinical Tools

Logo
OpiCalc
APGAR ScoreAssisted Delivery (FIGO)BPP (Manning Score)Bishop ScoreCARPREG II Cardiac RiskCervical Cancer StagingContraceptive Pearl IndexDoppler Matrix (UA/MCA)EFW (Hadlock)Endometrial StagingEndometrial ThicknessFGR Criteria (Consensus)FSFI (Sexual Function)Ferriman-Gallwey ScoreFetal Anemia (MCA PSV)GDM Diagnostic CriteriaGPA History IndicatorGail Model Breast RiskGestational Dating (LMP)HIV PMTCT ProtocolIOTA Simple RulesIVF Due Date & AMHIron Deficit (Ganzoni)Labour Progress (WHO)Maternal Sepsis (qSOFA)O-RADS ClassificationOvarian Cancer StagingPAS Hemorrhage RiskPPH Protocol (FIGO)Preeclampsia (ACOG)Rho(D) Dose (K-B)Rotterdam PCOS CriteriaSyphilis ManagementTORCH FrameworkVBAC Success ProbabilityVulvar Cancer StagingWeight Gain (IOM)mWHO Cardiac Risk

IVF Due Date & AMH

IVF Due Date Calculator

Based on Embryo Age at Transfer

AMH Ranges (Fertility)

Polycystic (PCOM)

> 3.3 ng/mL

Optimal / Normal

1.5–3.3 ng/mL

Low Reserve

0.7–1.5 ng/mL

Very Low Reserve

< 0.7 ng/mL

EVIDENCE SYNTHESIS

Clinical Reference Hub

Curated insights • How it Works • Practical Pearls • Evidence Base

CLINICAL INSIGHT

When to Use

Primary Clinical Uses

  • Accurately determining the Estimated Date of Delivery (EDD) and Estimated Gestational Age (EGA) for pregnancies conceived via In Vitro Fertilization.
  • Bypassing the standard Last Menstrual Period (LMP) method entirely due to ovulation induction suppression.
  • Interpreting Anti-Müllerian Hormone (AMH) levels for ovarian reserve testing.

The Dating Mandate

In an IVF pregnancy, the exact date of fertilization is a known scientific fact. Under no circumstances should early ultrasound/crown-rump length or LMP override the calculated IVF date. The IVF date is neurologically absolute.

CLINICAL INSIGHT

How it Works

Formula Rules

  • Standard Human Gestational Period = 280 days (from LMP) or 266 days (from conception).
  • For a Day 3 Embryo (Cleavage Stage): EDD = Transfer Date + 266 Days - 3 Days
  • For a Day 5 Embryo (Blastocyst): EDD = Transfer Date + 266 Days - 5 Days

AMH Interpretation

> 3.3 ng/mL
1.5 – 3.3 ng/mL
0.7 – 1.5 ng/mL
< 0.7 ng/mL
CLINICAL INSIGHT

Practical Pearls

Key Misconceptions

  • A very low AMH (<0.7) means the patient will have immense difficulty retrieving multiple eggs during IVF. It DOES NOT mean the patient cannot spontaneously get pregnant globally; egg quality is tied to age, not AMH pool size.
  • Oral contraceptive pills (OCPs) can artificially suppress AMH levels. If a patient gets an AMH tested while on the pill, the result is falsely terrifying.
CLINICAL INSIGHT

Next Steps

Obstetric Management of IVF Pregnancies

  • Continue progesterone supplementation through 10-12 weeks until the placenta takes over production (corpus luteum rescue).
  • Schedule a viability ultrasound at 7-8 weeks.
  • Offer fetal echocardiogram at 20-22 weeks due to the slightly increased background risk of congenital heart defects in IVF/ICSI neonates.
  • Monitor for preeclampsia (IVF with frozen embryo transfer strongly correlates with higher risk of hypertensive disorders of pregnancy).
CLINICAL INSIGHT

Evidence Base

ACOG Guidelines

Methods for Estimating the Due Date.

ACOG Committee Opinion No. 700.Obstet Gynecol.2017
CLINICAL INSIGHT

Background

Historical Context

The absolute precision of IVF dating revolutionized modern obstetrics, allowing clinicians to bypass the inherent unreliability of maternal menstrual history and identifying cases of true fetal growth restriction (FGR) with perfect denominators.