This tool supports structured infectious-disease decision making but does not replace clinician judgement or local guideline pathways.
This OpiCalc infectious-disease entry reflects commonly used guideline criteria and bedside risk features used in contemporary clinical practice.
Aminoglycoside Extended Interval: Hartford-style eligibility flags for once-daily aminoglycoside use.
Stable renal function
+2 Points
Pregnancy
-2 Points
Dialysis / severe renal failure
-3 Points
Endocarditis present
Extensive burns / cystic fibrosis
Gram-negative infection where synergy not required
Assessment Tier
Score 0
Assess patient-specific exclusions before using Hartford-style dosing.